Adjuvants- and vaccines-induced autoimmunity: animal models.
“Sometimes they [adjuvants] can reproduce human autoimmune diseases including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, autoimmune thyroiditis and antiphospholipid syndrome and may provide insights about the potential adverse effects of adjuvants.”
Autoimmune/Inflammatory Syndrome Induced by Adjuvants and Thyroid Autoimmunity.
Indeed, clinical cases of Hashimoto’s thyroiditis and/or subacute thyroiditis were observed after the exposure to vaccines as well as silicone implantation.
[Differential diagnosis of thyrotoxicosis in subjects with post-immunization reaction].
“An increasingly greater fraction of the general population is getting involved in the immunization program. However, conditions of individual subjects are not always properly evaluated prior to immunization. The clinical case reported below demonstrates the difficulty of diagnostic examination of patients with Graves disease (toxic goiter), endocrine ophthalmopathy, and post-immunization reaction.”
Lymphoid thyroiditis following immunization with group A streptococcal vaccine.
This evidence of thyroiditis produced by immunization against a nonthyroidal antigen suggests that some cases of Hashimoto’s thyroiditis in humans may result from nonspecific immune responses.
[Lymphoma of the thyroid in a patient with autoimmune thyroiditis and Sjögren’s syndrome–case report].
“As many years of immunisation may lead to carcinogenesis it is important to raise awareness among medical staff with regard to cases of chronic autoimmune disease.”
Subacute thyroiditis and dyserythropoesis after influenza vaccination suggesting immune dysregulation.
We describe a case of subacute thyroiditis and dyserythropoesis occurring shortly after administration of an influenza vaccine in a 55-year-old man with history of diabetes and psoriasis, family history of autoimmunity without clinical evidence of acute viral infection prior to the onset of symptoms.
Subacute thyroiditis (de Quervain’s) due to influenza A: presenting as fever of unknown origin (FUO).
“Influenza immunization or infection may cause subacute thyroiditis.”
Subacute thyroiditis following influenza vaccine (Vaxigrip) in a young female.
Subacute thyroiditis (SAT), also called de Quervain thyroiditis or granulomatous thyroiditis, is a self-limiting, possibly viral, and inflammatory thyroid disorder that is usually associated with thyroid pain and systemic symptoms. This report details a case of SAT possibly associated with influenza vaccine (Vaxigrip) in a young female.
Subacute thyroiditis following seasonal influenza vaccination.
SAT should be considered as a possible outcome following influenza vaccination and flu-like syndrome.
An unmasking phenomenon in an observational post-licensure safety study of adolescent girls and young women.
“Our recent experience in a post-licensure safety study of autoimmune conditions following the quadrivalent human papillomavirus vaccine in 189,629 girls and young women ages 9-26 years led us to question the adequacy of the exclusion of Day 0 events to prevent the erroneous association of prevalent conditions with vaccination. ”